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A ioimbina é um alcaloide indólico que atua primariamente como antagonista competitivo dos receptores α2-adrenérgicos pré-sinápticos, promovendo aumento da liberação de noradrenalina e intensificação da atividade simpática. Esse mecanismo resulta em efeitos fisiológicos como aumento da frequência cardíaca, pressão arterial e mobilização lipídica, sendo explorado em contextos clínicos e experimentais .
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