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Polifarmácia não significa simplesmente usar muitos medicamentos. O risco está na combinação entre múltiplos fármacos, características individuais do paciente, interações, alterações farmacocinéticas e farmacodinâmicas e dificuldades de adesão. Na enfermagem, a conciliação medicamentosa e o acompanhamento sistemático são fundamentais para identificar duplicidades, problemas de administração e possíveis eventos adversos, especialmente após mudanças na terapia. #enfermagem #saudedoidoso
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Qual a diferença entre Valproato e Divalproato de sódio? Ambas as formulações se transformam em ânion valproato no organismo, que é a forma ativa no fármaco. No entanto, o valproato de sódio já vem na forma de sal que logo se converte em ânion. Já na formulação de divalproato, ele tem composição 1:1 de valproato de sódio e ácido valproico. O Ácido valproico demora um tempo a mais para se transformar em ânion, do que o sal. Por isso, há uma pequena diferença farmacocinética no pico de concentraç...
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Você acerta essa questão de enfermagem?Farmacocinética ≠ farmacodinâmica!”
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