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Os calos são causados quando há uma compressão entre duas superfícies duras e a pele. A pele reage, causando um espessamento da sua camada superficial, uma camada chamada epiderme. E na epiderme há uma camada mais superficial ainda, que produz a queratina: chamada camada córnea. E o calo nada mais é do que um intenso espessamento da camada córnea da epiderme. Calo é uma quantidade exagerada e desproporcional de queratina. É a forma, ainda que nos pareça errada, que a pele encontra para se prote...
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