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Tumefações são protuberâncias rígidas com formato de cone na pele, comumente encontradas no topo da superfície do quinto pododáctilo, especialmente sobre a articulação. Os calos são espessamentos amplos e planos da pele geralmente localizados nas palmas ou solas. As tumefações podem ser dolorosas ou sensíveis, no entanto os calos geralmente não causam sintomas. Geralmente, as tumefações e os calos são causados pela fricção e pressão intermitentes, especialmente em pessoas que utilizam calçados.
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