Kwai Logo
Kwai User Avatar
A melanina é sintetizada nos melanócitos a partir da tirosina, por ação da tirosinase, gerando inicialmente DOPA e, em sequência, dopaquinona. A partir daí, a via segue para a formação de eumelanina ou feomelanina, com posterior transferência dos melanossomas para os queratinócitos. Esse processo não é isolado. Ele é regulado por sinalizações como a-MSH, ativação do receptor MC1R, expressão de MITF e estímulos inflamatórios e oxidativos que aumentam a atividade melanogênica. É aqui que entram os
41
1
Baixar
O câncer de pele melanoma tem origem nos melanócitos e é mais frequente em adultos brancos. O melanoma pode aparecer em qualquer parte do corpo, na pele ou mucosas, na forma de manchas, pintas ou sinais. Nos indivíduos de pele negra, ele é mais comum nas áreas claras, como palmas das mãos e plantas dos pés.
51
1
Baixar
Carregando
kwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwaikwai kwaikwaikwaikwaikwaikwaikwaikwaikwaikwai